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c. 865-925 CE

865 – 925

Muhammad ibn Zakariya al-Razi

Persian physician-philosopher of the Islamic Golden Age who advanced clinical medicine, pharmacology, and critical inquiry.

About Muhammad ibn Zakariya al-Razi

Muhammad ibn Zakariya al-Razi was born around 865 CE in Ray, Persia (near modern Tehran). Legend holds he came to medicine late, after first pursuing alchemy and music, but once committed, he became the most influential clinician of the Islamic Golden Age. He directed hospitals in Ray and later in Baghdad, where he reportedly selected the hospital site by scientific method: hanging pieces of meat throughout the city and choosing the location where decay was slowest. His Al-Hawi (The Comprehensive Book) was a massive medical encyclopedia, twenty-three volumes gathering Greek, Persian, Indian, and Arabic medical knowledge alongside his own clinical observations. It was translated into Latin as 'Liber Continens' and used in European medical schools for centuries. His treatise on smallpox and measles was the first to clinically differentiate the two diseases, a landmark in diagnostic medicine.

Best for

Evidence & Method

Turning observation into reliable knowledge

Ethics of Inquiry

Linking character with trustworthy practice

Knowledge Systems

Building case-based repositories that compound

What you can learn

  • Design evidence-gathering that separates observation from opinion
  • Use differential signs to discriminate similar phenomena
  • Structure case notes for cumulative learning
  • Balance skepticism with respect for tradition
  • Link ethics with practice in scientific work
  • Apply systematic experimentation to validate theoretical claims

Questions to ask al-Razi

Try these conversation starters, or ask anything you're curious about.

Starter

  • How do I test a claim when I only have simple tools and my own observations
  • What should I record in my notes to actually learn from experience over time
  • How do I respectfully question an expert without dismissing everything they taught

Deeper

  • How do I tell the difference between two things that look similar at first glance
  • What makes some evidence decisive and other evidence merely suggestive
  • How do I organize observations so that someone else could repeat what I did

Expert

  • How would you design a fair comparison between two different approaches
  • How do I build a knowledge system that compounds learning across many cases
  • What does the character of the inquirer have to do with the reliability of their findings

Example conversation with al-Razi

Topic: Questioning Authority Through Clinical Observation

You

You actually wrote a book called "Doubts about Galen." Wasn't Galen considered almost sacred in medicine back then?

al-Razi

He was indeed revered, and with good reason. Galen's anatomical and pharmacological work was extraordinary. But reverence must never silence inquiry. I observed cases at the hospital bedside that contradicted Galen's claims. When a patient's symptoms did not match what the great authority predicted, I had a choice: trust the authority or trust the evidence before my eyes. I chose the evidence. My Shukuk was not an attack on Galen but a demonstration that even the greatest physician must be tested against experience.

You

How did you approach distinguishing smallpox from measles? They must have looked very similar.

al-Razi

They do appear similar to the untrained eye, which is precisely why careful observation matters. I recorded the progression of each disease across many patients: the timing and character of the fever, the appearance and distribution of the skin eruptions, the sequence in which symptoms developed. Smallpox produces deeper, more uniform pustules that mature together, while measles presents a finer rash with different timing. These differential signs emerged not from theory but from sitting with patients, recording what I saw, and comparing cases over time.

You

What advice would you give to someone trying to build knowledge from observation in any field?

al-Razi

First, record everything with honesty, including your failures and uncertainties. My Al-Hawi contains cases where I was wrong, because errors properly documented teach as much as successes. Second, separate what you see from what you expect to see. Expectation is the great corrupter of observation. Third, organize your records so that patterns become visible across many instances. A single case proves little; a hundred cases recorded with care reveal the truth that no single authority could supply. And fourth, never let reputation, yours or another's, stand between you and the evidence.

Key ideas

  • Experience and reason must test inherited authority.
  • Clear differential signs turn confusion into diagnosis.
  • Case histories, well kept, become collective knowledge.
  • Ethics and character shape the reliability of inquiry.

How to apply

  • Run small, controlled comparisons before scaling decisions.
  • Standardize observation logs to enable replication.
  • Separate decisive indicators from incidental noise.
  • Tie practitioner incentives to truth-seeking behavior.

Intellectual approach

EmpiricalRationalistPragmaticSkeptical

Sources & further reading

Primary sources

  • Al-Hawi (The Comprehensive Book)
  • Kitab al-Mansuri (The Book to al-Mansur)
  • Al-Judari wa-l-Hasbah (On Smallpox and Measles)
  • Shukuk ‘ala Jalinus (Doubts about Galen)
  • Al-Tibb al-Ruhani (Spiritual Physick)
  • Kitab al-Asrar (Book of Secrets)

Recommended reading

  • The Spiritual Physick of Rhazes - trans. A. J. Arberry
  • On Smallpox and Measles - trans. W. A. Greenhill
  • Encyclopaedia Iranica: “Rāzī, Abū Bakr Moḥammad b. Zakariyyāʾ”
  • Britannica entry on Rhazes (al-Razi)

Influences

  • Hippocrates
  • Galen
  • Aristotle

Contemporaries

  • Qusta ibn Luqa
  • Al-Farabi (near-contemporary)
  • Hunayn ibn Ishaq (earlier influence)

Read more on Wikipedia →

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Frequently asked questions

What can I learn from chatting with AI Muhammad ibn Zakariya al-Razi?

Muhammad ibn Zakariya al-Razi was persian physician-philosopher of the Islamic Golden Age who advanced clinical medicine, pharmacology, and critical inquiry. Through an AI-powered conversation, you can explore their ideas, test theories, and build deeper understanding of their historical context.

What are good questions to ask AI al-Razi?

Great starter questions include: "How do I test a claim when I only have simple tools and my own observations" You can also explore deeper topics or expert-level discussions tailored to your interests.

Is the AI al-Razi historically accurate?

The AI al-Razi is grounded in documented historical sources, including Al-Hawi (The Comprehensive Book) and Kitab al-Mansuri (The Book to al-Mansur). Responses reflect documented beliefs, speaking style, and historical context. Always verify key facts with primary sources for academic work.

What is AI al-Razi best for?

Evidence & Method: Turning observation into reliable knowledge. Ethics of Inquiry: Linking character with trustworthy practice. Knowledge Systems: Building case-based repositories that compound.

Can I chat with AI al-Razi for free?

Yes, you can start a conversation with AI al-Razi with a free HistorIQly account. Free users get 8 messages per day. For more messages and advanced features, upgrade to Premium or Pro.

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AI recreation based on historical sources. Not a substitute for professional advice.